Testosterone Replacement Therapy Department of Urology Side Effects of Testosterone Injections You might also notice you gain more muscle mass and lose body fat. This measures free testosterone plus testosterone attached to a blood protein called albumin. This is not a common test, but it can be given to check for certain medical conditions. Testosterone does decline in women as they age, especially after menopause, but most of the time, TRT is not needed. Doctors also play an important role in monitoring the safety of hormone therapies and any side effects that develop. It is advisable that people with any severe side effects contact their doctor as soon as they can. To balance hormones and support treatment for symptoms of low testosterone in men, Anastrozole (generic Arimidex) reduces estrogen levels and the conversion of testosterone to estrogen. By boosting your body’s production of testosterone, clomiphene citrate (generic Clomid®) increases energy and improves mood and focus while preserving fertility. Testosterone is formed via the hypothalamic–pituitary–gonadal (HPG)axis. The U.S. Food and Drug Administration clarified in 2015 that prescribing testosterone for low testosterone levels due to aging constitutes off-label use. Inconsistent dosing or missed injections can lead to testosterone fluctuations, causing mood swings, fatigue, and energy crashes. Therefore, selecting a dosing schedule that aligns with one’s lifestyle is essential for treatment success. However, the Testosterone Trials were designed to assess only effectiveness and not the risks of testosterone therapy, including prostate cancer or cardiovascular disease. In addition, medical contraindications to testosterone therapy have to be dealt with before prescribing testosterone replacement therapy. These are medical issues that would increase the risks of testosterone replacement therapy or make it downright dangerous. Testosterone is present in both males and females, but the levels are higher in males. In all people, it performs many important functions, influencing sexual development, libido, mood, and more. According to GoodRx.com, the cost of 1 mL (200 mg/mL) marked decrease of the male hormone testosterone (docpulse.com) Depo-Testosterone is about $30. Hormone levels are tested and medications are administered to help hormones such as testosterone and thyroid reach their optimum levels. It is important to consider that everyone is different; blood testing your testosterone levels is only part of the story. A guy with a level of, say, 200 ng/dL will most likely feel symptoms of low testosterone, such as fatigue and low libido, whereas another with a level of 600 ng/dL may feel exactly the same. Selling or giving away this medicine may harm others and it is against the law. As with any medicine, the decision on whether the possible benefits outweigh any risks is up to you and your doctor. Oral testosterone has been around since the 1980s but was not popular because it can cause problems for the liver. But there are now some new pills (Jatenzo, Tlando, and Kyzatrex) that bypass the liver and get testosterone into the blood directly, in the same way that skin patches, gels, and other treatments do. A nurse or technician may